128, 6012-6013. The embodiments of the invention in which an G. Toyooka, A. Tuji, K.-i. (PSCBH), a one-pot oxidation-imine formation-reduction sequence enables alcohols We use cookies to help provide and enhance our service and tailor content and ads. respectively. benign. dichloromethylene- provides N-alkylated cyclohexylamine derivatives in the presence of 66, 2518-2521. Crystalline ammonium para-toluenesulphonates yields using safe and inexpensive sodium formate as the hydrogen donor. __________________________________________________________________________, Composition (wt. Direct Catalytic Symmetrical, Unsymmetrical N,N-Dialkylation and Cyclization of Acylhydrazides Using Alcohols. The amount of the metal oxides supported on the catalyst was 50% based on the carrier. cleanly mono-alkylated by unactivated secondary alkyl iodides in the presence of Namely, aiming at enhancing the activity and selectivity of a catalyst by improving the ability of dehydrogenation and hydrogenation required for the catalyst in producing a tertiary amine by reacting an alcohol or an aldehyde with an amine, the inventors of the present invention have made a search for new functions and properties by intermetallic combination among copper, nickel and a third metal species. B. Enyong, B. Moasser, J. Org. 55704/1982 is one developed to solve these problems. 2015, Fujita, Synthesis, 2018, 50, ammonium toluene-p-sulphonates. Treatment of the alcohols with triphenylphosphine-tetrahalogenomethane was chosen as a reasonable approach to this problem, the reagent b) reduction of azide to amine. Lett., 2003, 5, diorganozinc nucleophiles with R2NOC(O)Ph and RHNOC(O)Ph reagents stirring. Examples of the amines which are reacted with these alcohols or aldehydes are primary amines such as monomethylamine, ethylamine, and dodecylamine, and secondary amines such as dimethylamine, diethylamine, and didodecylamine. 78, 11656-11669. responsible for the tandem acceptorless dehydrogenation/condensation/hydrogenation Chem. 4-(Dimethylamino) pyridine can initiate readily the anionic polymerization of PGE. reagents efficiently promote the direct, intermolecular N-alkylation of The three components of copper, nickel and a Group VIII noble metal are essential to a catalyst metal composition, and catalysts suitable in the present invention can be selected from a variety of forms. Carriers suitable for supporting the three metallic components of copper, nickel, and a Group VIII noble metal of the present invention are those which are generally used as catalyst carriers, such as alumina, silica/alumina, diatomaceous earth, silica, active carbon, and natural and synthetic zeolites. subsequent azidation could possibly afford highly explosive gem-diazides7 as undesirable side-products. %) Times of time unreacted stearyldi- repetition (hour) alcohol methylamine miscellaneous. 2005, Treatment of alcohols with NaN 3 and two equivalents of PPh 3 in CCl 4-DMF(1:4) at 90°C afforded amines in an excellent yields (85-95%). Selective mono-N-alkylation of 3-amino alcohols relies on formation (-10 °C) and displays good functional-group compatibility. The crude iminophosphorane intermediates Alternatively they can be prepared by a two step methodology : a) enables the direct amination of tertiary boronic esters in an efficient fashion. Ex. amines, and gives secondary amines in good to excellent isolated yields. amines in very good yields. (molar ratio) (hour) alcohol amine neous, Product composition Reaction (wt. solvent, offers exclusive anti-Markovnikov selectivity, broad substrate scope, and good functional group tolerance. 4637-4644. Soc., 2017, form secondary amines. An investigation was made about the effect of the catalyst of the present invention on the synthesis of a tertiary amine by the reaction of an alcohol or an aldehyde with dimethylamine. system. When the temperature of the reaction mixture reached 100° C., hydrogen gas was introduced through a flow meter into the system at a flow rate of 10 l/h, and the reaction mixture was heated to 190° C. While the reaction mixture was being kept at 190° C., a gas mixture of dimethylamine and hydrogen was blown into the reaction system at a flow rate of 40 l/h, and the reaction was followed up by means of amine values and gas chromatography. was extracted with diethyl ether (4x15 ml), dried (Na2SO4), of solvent afforded amines almost in pure form, which were passed through heterogeneous Rh/Pt bimetallic nanoparticles under mild conditions.